Invitrogen™ AGR2 Monoclonal Antibody (10E2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA516244

Catalog No. PIMA516244

Description

AGR2 Monoclonal Antibody for Western Blot, IHC (P)

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

Specifications

• Antigen: AGR2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: O88312, O95994
• Gene Symbols: Agr2
• Immunogen: A portion of amino acids 50-100 of human AGR2 was used as the immunogen for the antibody.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Monkey, Bovine, Horse
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 10E2
• Conjugate: Unconjugated
• Gene: Agr2
• Gene Alias: AG2; AG-2; AGR2; agr2 protein; Agr2h; AII; AII type II arginase; anterior gradient 2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient 2, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient protein 2 homolog; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; epididymis secretory protein Li 116; Gob4; Gob-4; HAG-2; HEL-S-116; HPC8; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; mAG-2; nonhepatic arginase; Non-hepatic arginase; PDIA17; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; Type II arginase; UNQ515/PRO1030; XAG-2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100053075, 10551, 23795, 298961, 415112, 482333
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid