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Invitrogen™ AGR2 Monoclonal Antibody (GT5812)
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Catalog No. PIMA531574
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100 μL
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PIMA531574 100 μL
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Catalog No. PIMA531574 Supplier Invitrogen™ Supplier No. MA531574
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Description

Mouse Monoclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (82%), Pig (96%), Rhesus Monkey (99%), Bovine (95%). Positive Control: MCF-7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGR2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT5812
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Agr2
Gene Accession No. O95994
Gene Alias AG2; AG-2; AGR2; agr2 protein; Agr2h; AII; AII type II arginase; anterior gradient 2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient 2, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient protein 2 homolog; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; epididymis secretory protein Li 116; Gob4; Gob-4; HAG-2; HEL-S-116; HPC8; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; mAG-2; nonhepatic arginase; Non-hepatic arginase; PDIA17; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; Type II arginase; UNQ515/PRO1030; XAG-2
Gene Symbols Agr2
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human Anterior Gradient 2. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10551
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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