Invitrogen™ AGR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585636

Catalog No. PIPA585636

Description

Keep as concentrated solution. Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (82%), Pig (96%), Rhesus Monkey (99%), Bovine (95%). Positive Control: MCF-7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

Specifications

• Antigen: AGR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Agr2
• Gene Alias: AG2; AG-2; AGR2; agr2 protein; Agr2h; AII; AII type II arginase; anterior gradient 2; anterior gradient 2 homolog; anterior gradient 2 homologue; anterior gradient 2, protein disulphide isomerase family member; anterior gradient homolog 2; anterior gradient protein 2 homolog; ARG2; arginase 2; arginase II; arginase type II; arginase, type II; arginase-2, mitochondrial; AU022422; epididymis secretory protein Li 116; Gob4; Gob-4; HAG-2; HEL-S-116; HPC8; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; mAG-2; nonhepatic arginase; Non-hepatic arginase; PDIA17; protein disulfide isomerase family A, member 17; protein Gob-4; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; Type II arginase; UNQ515/PRO1030; XAG-2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10551, 23795
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.203 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O88312, O95994
• Gene Symbols: Agr2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Anterior Gradient 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG