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AGR2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501727852 Shop All Proteintech Group Inc Products
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50-172-7852 150 μL
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Catalog No. 50-172-7852 Supplier Proteintech Group Inc Supplier No. 122751AP150UL
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Rabbit Polyclonal Antibody

AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).

Specifications

Antigen AGR2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene AGR2
Gene Accession No. O88312, O95994
Gene Alias AG 2, AG2, AGR2, GOB 4, HAG 2, HPC8, PDIA17, XAG 2
Gene Symbols AGR2
Host Species Rabbit
Immunogen AGR2 Fusion Protein Ag2919
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10551, 23795, 298961
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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