Invitrogen™ AgRP Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547831

Catalog No. PIPA547831

Description

In direct ELISAs, less than 25% cross-reactivity with recombinant human AgRP is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

Specifications

• Antigen: AgRP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Agrp
• Gene Alias: agouti related neuropeptide; agouti related protein; agouti related protein homolog; agouti-related protein; Agrp; AGRT; ART; ASIP2; orexigenic neuropeptide
• Host Species: Goat
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11604
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P56473
• Gene Symbols: Agrp
• Immunogen: Sf 21-derived recombinant mouse AgRP/ART Val25-Thr131.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG