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Invitrogen™ AgRP Polyclonal Antibody
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Catalog No. PIPA547895
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100 μg
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Catalog No. Quantity
PIPA547895 100 μg
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Catalog No. PIPA547895 Supplier Invitrogen™ Supplier No. PA547895
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Description

Goat Polyclonal Antibody

In Western blots, approximately 40% cross-reactivity with recombinant mouse AgRP/ART is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AgRP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Agrp
Gene Accession No. O00253
Gene Alias agouti related neuropeptide; agouti related protein; agouti related protein homolog; agouti-related protein; Agrp; AGRT; ART; ASIP2; orexigenic neuropeptide
Gene Symbols Agrp
Host Species Goat
Immunogen Sf 21-derived recombinant human AgRP/ART Ala21-Thr132.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 181
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

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