Invitrogen™ AgRP Polyclonal Antibody

Guinea Pig Polyclonal Antibody

Supplier:  Invitrogen™ PA118414

Catalog No. PIPA118414

Description

Reconstitute in 50 μL sterile water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8 °C. It is recommended that a thawed sample is stored at 4 °C for no longer than 2 weeks. Allocation of appropriate anti-bacterial agent can increase shelf life by several weeks. Diluted serum should be prepared as required. Long term stability requires storage, preferably in small aliquots at -20 °C or lower. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this.

Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

Specifications

• Antigen: AgRP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Agrp
• Gene Alias: agouti related neuropeptide; agouti related protein; agouti related protein homolog; agouti-related protein; Agrp; AGRT; ART; ASIP2; orexigenic neuropeptide
• Host Species: Guinea Pig
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Sheep
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Concentration: Conc. Not Determined
• Formulation: whole serum with no preservative
• Gene Accession No.: O00253, P56473
• Gene Symbols: Agrp
• Immunogen: Synthetic peptide corresponding to a region (82-131) within the carboxy domain of mouse agouti related protein conjugated to carrier protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 11604, 181, 25582, 443269
• Content And Storage: 4°C
• Form: Lyophilized

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov