Invitrogen™ AGTR1 Monoclonal Antibody (11B3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA542535

Catalog No. PIMA542535

Description

Positive Control: PC-12 cell lysate, A549 cell lysate, HepG2 cell lysate, Hela cell lysate, PC-12, 293T, A549. Subcellular Location: Cell membrane, Membrane.

AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

Specifications

• Antigen: AGTR1
• Classification: Monoclonal
• Concentration: 8.794 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P25095, P29754, P30556
• Gene Symbols: AGTR1, Agtr1a
• Immunogen: Synthetic peptide within human Angiotensin II Type 1 Receptor aa 300-350.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 11B3
• Conjugate: Unconjugated
• Gene: AGTR1
• Gene Alias: 1810074K20Rik; AG2S; AGTR1; Agtr1a; Agtr-1a; AGTR1B; AI551199; angiotensin II receptor type 1; angiotensin II receptor, type 1; angiotensin II receptor, type 1a; Angiotensin II type-1 receptor; Angiotensin II type-1A receptor; angiotensin receptor 1; angiotensin receptor 1a; Angtr-1a; AT1; At1a; AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1B; HAT1R; Type-1 angiotensin II receptor; Type-1A angiotensin II receptor; type-1B angiotensin II receptor; vascular type-1 angiotensin II receptor
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 11607, 185, 24180
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid