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Invitrogen™ AGTR1 Monoclonal Antibody (11B3)
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Catalog No. PIMA542535
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100 μL
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PIMA542535 100 μL
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Catalog No. PIMA542535 Supplier Invitrogen™ Supplier No. MA542535
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Description

Mouse Monoclonal Antibody

Positive Control: PC-12 cell lysate, A549 cell lysate, HepG2 cell lysate, Hela cell lysate, PC-12, 293T, A549. Subcellular Location: Cell membrane, Membrane.

AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGTR1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 11B3
Concentration 8.794 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene AGTR1
Gene Accession No. P25095, P29754, P30556
Gene Alias 1810074K20Rik; AG2S; AGTR1; Agtr1a; Agtr-1a; AGTR1B; AI551199; angiotensin II receptor type 1; angiotensin II receptor, type 1; angiotensin II receptor, type 1a; Angiotensin II type-1 receptor; Angiotensin II type-1A receptor; angiotensin receptor 1; angiotensin receptor 1a; Angtr-1a; AT1; At1a; AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1B; HAT1R; Type-1 angiotensin II receptor; Type-1A angiotensin II receptor; type-1B angiotensin II receptor; vascular type-1 angiotensin II receptor
Gene Symbols AGTR1, Agtr1a
Host Species Mouse
Immunogen Synthetic peptide within human Angiotensin II Type 1 Receptor aa 300-350.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11607, 185, 24180
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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