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Invitrogen™ AGTR1 Polyclonal Antibody
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Catalog No. PIPA578742
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100 μg
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PIPA578742 100 μg
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Catalog No. PIPA578742 Supplier Invitrogen™ Supplier No. PA578742
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HEK293 whole cell, human T-47D whole cell, human PC-3 whole cell, human U-87MG whole cell, human HepG2 whole cell, monkey COS-7 whole cell, rat brain tissue, rat liver tissue, rat kidney tissue, rat RH35 whole cell, mouse brain tissue, mouse liver tissue, mouse kidney tissue, mouse HEPA1-6 whole cell. IHC: human mammary cancer tissue.

AGTR1 is known as Angiotensin II Type 1 Receptor. Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. And it acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. Moreover, this gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGTR1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene AGTR1
Gene Accession No. P25095, P29754, P30556
Gene Alias 1810074K20Rik; AG2S; AGTR1; Agtr1a; Agtr-1a; AGTR1B; AI551199; angiotensin II receptor type 1; angiotensin II receptor, type 1; angiotensin II receptor, type 1a; Angiotensin II type-1 receptor; Angiotensin II type-1A receptor; angiotensin receptor 1; angiotensin receptor 1a; Angtr-1a; AT1; At1a; AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1B; HAT1R; Type-1 angiotensin II receptor; Type-1A angiotensin II receptor; type-1B angiotensin II receptor; vascular type-1 angiotensin II receptor
Gene Symbols AGTR1, Agtr1a
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human AGTR1 (1-28aa MILNSSTEDGIKRIQDDCPKAGRHNYIF).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11607, 185, 24180
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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