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Invitrogen™ AGTR2 Recombinant Rabbit Monoclonal Antibody (0V7Y3)
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Catalog No. PIMA538084
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PIMA538084 100 μL
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Catalog No. PIMA538084 Supplier Invitrogen™ Supplier No. MA538084
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, 293T, PC-12, HepG2, Mouse brain, Mouse kidney, Mouse uterus, Rat liver Immunogen sequence: AFIICWLPFH VLTFLDALAW MGVINSCEVI AVIDLALPFA ILLGFTNSCV NPFLYCFVGN RFQQKLRSVF RVPITWLQGK RESMSCRKSS SLREMETFVS.

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AGTR2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 0V7Y3
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Agtr2
Gene Accession No. P35351, P35374, P50052
Gene Alias AGTR2; AI316812; Angiotensin ii at2; angiotensin II receptor type 2; angiotensin II receptor, type 2; angiotensin II type 2 receptor; angiotensin II type-2 receptor; angiotensin receptor 2; AT>sub>2>/sub>R; AT2; AT2 receptor; AT2R; AT2-R; ATGR2; AW107640; MRX88; type-2 angiotensin II receptor
Gene Symbols Agtr2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 264-363 of human AGTR2 (P50052).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11609, 186, 24182
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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