Invitrogen™ AGTR2 Recombinant Rabbit Monoclonal Antibody (SN71-03)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532293

Catalog No. PIMA532293

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Specifications

• Antigen: AGTR2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P35351, P35374, P50052
• Gene Symbols: Agtr2
• Immunogen: Synthetic peptide within Human Angiotensin II Type 2 Receptoraa 311-363.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: SN71-03
• Conjugate: Unconjugated
• Gene: Agtr2
• Gene Alias: AGTR2; AI316812; Angiotensin ii at2; angiotensin II receptor type 2; angiotensin II receptor, type 2; angiotensin II type 2 receptor; angiotensin II type-2 receptor; angiotensin receptor 2; AT>sub>2>/sub>R; AT2; AT2 receptor; AT2R; AT2-R; ATGR2; AW107640; MRX88; type-2 angiotensin II receptor
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 11609, 186, 24182
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid