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Invitrogen™ AHA1 Monoclonal Antibody (4F3-B6)
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Catalog No. PIMA521096
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100 μg
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Catalog No. Quantity
PIMA521096 100 μg
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Catalog No. PIMA521096 Supplier Invitrogen™ Supplier No. MA521096
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MAKWGEGDPR WIVEERANAT NVNNWHWTER DASNWSTDKL KTLFLAVQVQ NEEGKCEVTE VSKLDGEASI NNRKGKLIFF YEWSVKLNWT GTSKSGVQYK GHVEIPNLSG ENSVDEVEIS VSLAKDEPDT NLVALMKEEG VKLLREAMGI YISTLKTEFT QGMILPTMNG ESVDPVGQPA LKTEERKAKP APSKTQARPV GVKIPTCKIT LKETFLTSPE ELYRVFTTQE LVQAFTHAPA TLEADRGGKF HMVDGNVSGE FTDLVPEKHI VMKWRFKSWP EGHFATITLT FIDKNGETEL CMEGRGIPAP EEERTRQGWQ RYYFEGIKQT FGYGARLF.

Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen AHA1
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 4F3-B6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Ahsa1
Gene Accession No. O95433
Gene Alias Activator of 90 kDa heat shock protein ATPase homolog 1; activator of Hsp90 ATPase activity 1; Activator of Hsp90 ATPase protein 1; Aha 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); AHA1, activator of heat shock protein ATPase 1; AHA1, activator of heat shock protein ATPase homolog 1; Aha1p; AHSA 1; Ahsa1; BC023857; C14orf3; hAha1; Hsp90 co-chaperone AHA1; HSPC322; p38; SHSA1; YD8142.16; YD8142B.06; YDR214W
Gene Symbols Ahsa1
Host Species Mouse
Immunogen AHSA1 (AAH00321, 1 a.a. ~ 338 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10598
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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