AIF-1/Iba1, Mouse anti-Human, Alexa Fluor 532, Clone: rAIF1/1909, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP275760AF532
DescriptionAIF-1/Iba1 Monoclonal antibody specifically detects AIF-1/Iba1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).
|50mM Sodium Borate with 0.05% Sodium Azide|
|AIF-1/Iba1 Antibody (rAIF1/1909) was developed against purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary)|
|Protein A or G purified|
|Store at 4°C in the dark.|
|AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).|
|Alexa Fluor 532|
|AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1|
|Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience|
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