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Tocris Bioscience™ AIM 100
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Catalog No. 494650
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494650 50 mg
49-461-0 10 mg
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Catalog No. 494650 Supplier Tocris Bioscience™ Supplier No. 4946/50
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Description

Potent and selective Ack1 (TNK2) inhibitor

Potent Ack1 (TNK2) inhibitor (IC50 = 22 nM). Exhibits selectivity for Ack1 over ABL1, BTK, Lck and LYN; exhibits no inhibition of 25 other kinases. Suppresses phosphorylation of Tyr267 of the androgen receptor in prostate cancer cells. Also suppresses growth of radioresistant castration-resistant prostate cancer in xenograft tumors in mice.

Chemical Identifiers

CAS 873305-35-2
Molecular Formula C23H21N3O2

Specifications

Quantity 50 mg
Formula Weight 371.43
Molecular Weight (g/mol) 371.44
Chemical Name or Material AIM 100

Safety and Handling

Recommended Storage Store at +4°C
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