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Invitrogen™ AKAP12 Monoclonal Antibody (OTI1B6)
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Catalog No. PIMA527420
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100 μL
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PIMA527420 100 μL
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Catalog No. PIMA527420 Supplier Invitrogen™ Supplier No. MA527420
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Description

Mouse Monoclonal Antibody

AKAP12 Monoclonal Antibody for Western Blot, IHC (P)

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKAP12
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1B6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AKAP12
Gene Accession No. Q02952
Gene Alias A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AI317366; AKAP 250; AKAP12; AKAP-12; AKAP12A; AKAP12B; AKAP12G; AKAP250; A-kinase anchor protein 12; A-kinase anchor protein 250 kDa; A-kinase anchor protein, 250kDa; A-kinase anchoring protein 12; Gag12; gercelin; germ cell lineage protein gercelin; Gravin; kinase scaffold protein gravin; Myasthenia gravis autoantigen; myasthenia gravis autoantigen gravin; Srcs5; Src-Suppressed C Kinase Substrate; SSeCKS; SSeCKS, Gravin, AKAP250; testis specific gene A12; Tsga12; v-src suppressed transcript 5
Gene Symbols AKAP12
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 266-557 of AKAP12 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9590
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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