AKAP12 Mouse anti-Human, Clone: OTI1B6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811208

Catalog No. 50-167-0523

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Specifications

• Antigen: AKAP12
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: AKAP12
• Gene Alias: AKAP250, SSeCKS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9590
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1B6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q02952
• Gene Symbols: AKAP12
• Immunogen: Human recombit protein fragment corresponding to amino acids 266-557 of human AKAP12 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b