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Invitrogen™ AKAP12 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA129372

Catalog No. PIPA129372


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Description

Description

PA1-29372 detects SSecks from rat samples.

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

AKAP12
Polyclonal
Unconjugated
AKAP12
A kinase (PRKA) anchor protein (gravin) 12; A kinase (PRKA) anchor protein 12; AI317366; AKAP 250; AKAP12; AKAP-12; AKAP12A; AKAP12B; AKAP12G; AKAP250; A-kinase anchor protein 12; A-kinase anchor protein 250 kDa; A-kinase anchor protein, 250kDa; A-kinase anchoring protein 12; Gag12; gercelin; germ cell lineage protein gercelin; Gravin; kinase scaffold protein gravin; Myasthenia gravis autoantigen; myasthenia gravis autoantigen gravin; Srcs5; Src-Suppressed C Kinase Substrate; SSeCKS; SSeCKS, Gravin, AKAP250; testis specific gene A12; Tsga12; v-src suppressed transcript 5
Sheep
Ammonium sulfate precipitation
RUO
83425
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry, Immunoprecipitation, Western Blot
1 mg/mL
PBS with 0.08% sodium azide
Q5QD51
AKAP12
Rat SSecks fragment corresponding to amino acid 620-1596.
125 μg
Primary
Rat
Antibody
IgG
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