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AKAP12 Rabbit anti-Human, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501734781 Shop All Proteintech Group Inc Products
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50-173-4781 150 μL
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Catalog No. 50-173-4781 Supplier Proteintech Group Inc Supplier No. 251991AP150UL
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Description

Rabbit Polyclonal Antibody

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Specifications

Antigen AKAP12
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene AKAP12
Gene Accession No. Q02952, Q5QD51
Gene Alias A kinase anchor protein 12, AKAP 12, AKAP 250, AKAP12, AKAP250, Gravin, Myasthenia gravis autoantigen
Gene Symbols AKAP12
Host Species Rabbit
Immunogen AKAP12 Fusion Protein Ag17769
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83425, 9590
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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