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AKAP8/AKAP95 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
$151.31 - $568.26
Specifications
| Antigen | AKAP8/AKAP95 |
|---|---|
| Applications | Immunohistochemistry |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Form | Liquid |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-157-1698
|
Bethyl Laboratories, Inc
IHC00217T |
10 μL |
Each for $151.31
|
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50-157-1697
|
Bethyl Laboratories, Inc
IHC00217 |
100 μL |
Each for $568.26
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Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Gorilla and Chimpanzee
The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. The family of RII-anchoring proteins has been designated A-kinase anchoring proteins (AKAP). AKAP 95, also known as AKAP 8, is a nuclear matrix protein predomitly expressed in liver, heart, pancreas, kidney and skeletal muscle. During mitosis, AKAP 95 is recruited to the chromosomes and plays an essential role in mitotic progression. Characteristic of its family, AKAP 95 participates in PKA signaling through an interaction with the RII regulatory subunit. In addition, AKAP 95 forms a complex with HA95 and HDAC3 and is required for the deacetylation of Histone H3 in mitosis.Specifications
| AKAP8/AKAP95 | |
| Polyclonal | |
| Liquid | |
| RUO | |
| TBS with 0.1% BSA and 0.09% sodium azide | |
| AKAP8; AKAP95; DKFZp586B1222; A kinase (PRKA) anchor protein 8; A kinase anchor protein 95; A-kinase anchor protein 8; A-kinase anchor protein, 95kDa | |
| Between 642 and C-term | |
| Primary | |
| 4° C | |
| AKAP8 |
| Immunohistochemistry | |
| Unconjugated | |
| Rabbit | |
| Human, Mouse | |
| O43823, Q9DBR0 | |
| 10270, 56399 | |
| IgG | |
| Antigen affinity chromatography | |
| Antibody |
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