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AKIP Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986040
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50-198-6040 100 μL
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Catalog No. 50-198-6040 Supplier Bioss Supplier No. BS4287R
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Description

Rabbit Polyclonal Antibody

Aurora A is a 46 kDa protein that plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Multiple transcript variants encoding the same protein have been found for this gene. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal.

Specifications

Antigen AKIP
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene AURKA
Gene Accession No. O14965
Gene Alias Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; Aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; Aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; BOS_13320; Breast tumor-amplified kinase; BTAK; CR956640.2; EC 2.7.11.1; hARK1; IAK; Iak1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; Stk15; Stk6; STK7
Gene Symbols AURKA
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human AKIP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6790
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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