Invitrogen™ AKR1C1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA586835

Catalog No. PIPA586835

Description

Purity is > 95% by SDS-PAGE.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Specifications

• Antigen: AKR1C1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AKR1C1
• Gene Alias: 17-beta-HSD 5; 17HSD type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3alpha-HSD; Akr1c1; Akr1c6; aldo-keto reductase C; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (aldehyde reductase); aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; estradiol 17 beta-dehydrogenase 5; estradiol 17-beta-dehydrogenase (A-specific); H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity hepatic bile acid-binding protein; Hsd17b5; hydroxysteroid 17-beta dehydrogenase 5; indanol dehydrogenase; MBAB; RP11-69D4.1; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type 5 17beta-hydroxysteroid dehydrogenase; type II 3-alpha-hydroxysteroid dehydrogenase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1645, 307092, 83702
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P70694, Q04828
• Gene Symbols: AKR1C1, Akr1c6
• Immunogen: A synthetic peptide corresponding to residues in Human AKR1C1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov