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Invitrogen™ AKR1C2 Polyclonal Antibody
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Catalog No. PIPA536572
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100 μL
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PIPA536572 100 μL
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Catalog No. PIPA536572 Supplier Invitrogen™ Supplier No. PA536572
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 37 kDa. Purity is >95% by SDS-PAGE.

DD1 is also designated AKR1C1, DDH or DDH1, while DD2 also can be designated AKR1C2, dDD, BABP or DDH2. AKR1C3 and 3 alpha-HSD are alternate designations for human DD3 (which is referred to as AKR1C18 in rodents), while DD4 also can be called AKR1C4, CD, CHDR or AKR1C6 (in rodents). DD1 and DD2 are 20 alpha-HSDs, whereas DD3 and DD4 are the 3 alpha- HSDs. The multiple human cytosolic dihydrodiol dehydrogenases are involved in the metabolism of xenobiotics, such as polycyclic aromatic hydrocarbons, pesticides and steroid hormones, and are responsible for the reduction of ketone-containing drugs by using NADH or NADPH as a cofactor. The 20 alpha- HSD catalyzes the reaction of Progesterone to the inactive form 20 alpha-hydroxyprogesterone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKR1C2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene AKR1C2
Gene Accession No. P52895, Q6AYQ2, Q91WR5
Gene Alias 17-alpha-HSD; 17-alpha-hydroxysteroid dehydrogenase; 3 alpha-HSD3; 3(17)alpha-hydroxysteroid dehydrogenase; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-HSD3; 3-alpha-hydroxysteroid dehydrogenase; 9430025F20Rik; AI315367; AKR1C2; Akr1c21; AKR1C-pseudo; Aldo-keto reductase family 1 member C2; aldo-keto reductase family 1 member C21; aldo-keto reductase family 1, member C2; aldo-keto reductase family 1, member C21; BABP; Chlordecone reductase homolog HAKRD; DD; DD/BABP; DD1; DD2; DD-2; DD3; DDH2; Dihydrodiol dehydrogenase 2; dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III; dihydrodiol dehydrogenase type 1; Dihydrodiol dehydrogenase type 3; Dihydrodiol dehydrogenase/bile acid-binding protein; HAKRD; HBAB; HSD3-3 alpha; HSD3-alpha3; MCDR2; pseudo-chlordecone reductase; SRXY8; TDD; testicular 17,20-desmolase deficiency; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type II dihydrodiol dehydrogenase; Type III 3-alpha-hydroxysteroid dehydrogenase
Gene Symbols AKR1C2, Akr1c21
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 50-100 of human DD2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1646, 291283, 77337
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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