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Invitrogen™ AKR1C3 Polyclonal Antibody
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Catalog No. PIPA518339
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100 μg
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Catalog No. Quantity
PIPA518339 100 μg
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Catalog No. PIPA518339 Supplier Invitrogen™ Supplier No. PA518339
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

AKR1C3 a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKR1C3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene AKR1C3
Gene Accession No. P42330
Gene Alias 17-beta-HSD 5; 17beta-HSD5; 17-beta-hydroxysteroid dehydrogenase type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; 20-alpha-hydroxysteroid dehydrogenase; 20alpha-hydroxysteroid dehydrogenase; 2-dih; 3-alpha hydroxysteroid dehydrogenase, type II; 3-alpha-HSD type 2; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; Akr1c18; AKR1C3; Aldo-keto reductase family 1 member C18; aldo-keto reductase family 1 member C3; aldo-keto reductase family 1, member C18; aldo-keto reductase family 1, member C3; aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II); chlordecone reductase homolog HAKRb; DD3; DD-3; DDH1; DDX; Dihydrodiol dehydrogenase 3; Dihydrodiol dehydrogenase type I; dihydrodiol dehydrogenase X; HA1753; HAKRB; HAKRe; hluPGFS; HSD1; HSD17B5; Indanol dehydrogenase; KIAA0119; PGFS; prostaglandin F synthase; Testosterone 17-beta-dehydrogenase 5; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; type IIb 3-alpha hydroxysteroid dehydrogenase
Gene Symbols AKR1C3
Host Species Goat
Immunogen Synthetic peptide sequence (CFASHPNYPYSDEY) corresponding to the C-terminus amino acids of AKR1C3 (aa 311-323).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8644
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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