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Invitrogen™ AKR1C4 Polyclonal Antibody
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Catalog No. PIPA518511
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100 μg
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PIPA518511 100 μg
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Catalog No. PIPA518511 Supplier Invitrogen™ Supplier No. PA518511
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Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AKR1C4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene AKR1C4
Gene Accession No. P17516
Gene Alias 3-alpha-HSD; 3-alpha-HSD1; 3-alpha-hydroxysteroid dehydrogenase type I; AKR1C4; Aldo-keto reductase family 1 member C4; aldo-keto reductase family 1, member C4; C11; CDR; CHDR; Chlordecone reductase; chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4; DD4; DD-4; Dihydrodiol dehydrogenase 4; dihydrodiol dehydrogenase isozyme DD4; HAKRA; HGNC:387; MGC22581; type I 3-alpha-hydroxysteroid dehydrogenase
Gene Symbols AKR1C4
Host Species Goat
Immunogen Synthetic peptide sequence (DPKYQRVELNDGH) corresponding to the N-terminus amino acids of AKR1C4 (aa 2-15).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1109
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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