Invitrogen™ AKR1C4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103590

Catalog No. PIPA5103590

Description

Antibody detects endogenous levels of total AKR1C4.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Specifications

• Antigen: AKR1C4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AKR1C4
• Gene Alias: 3-alpha-HSD; 3-alpha-HSD1; 3-alpha-hydroxysteroid dehydrogenase type I; AKR1C4; Aldo-keto reductase family 1 member C4; aldo-keto reductase family 1, member C4; C11; CDR; CHDR; Chlordecone reductase; chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4; DD4; DD-4; Dihydrodiol dehydrogenase 4; dihydrodiol dehydrogenase isozyme DD4; HAKRA; HGNC:387; MGC22581; type I 3-alpha-hydroxysteroid dehydrogenase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1109
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P17516
• Gene Symbols: AKR1C4
• Immunogen: A synthesized peptide derived from human AKR1C4(Accession P17516), corresponding to amino acid residues M1-N32.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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