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AKT Polyclonal Antibody, Rockland™
SDP

Catalog No. 501990928
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100 μg
25 μL
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Catalog No. Quantity
50-199-0928 25 μL
50-199-0927 100 μg
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Catalog No. 50-199-0928 Supplier Rockland Immunochemicals Supplier No. 200401N98S
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Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. AKT Antibody reacts with the AKT from human tissues. Based on sequence we expect this antibody to react as well with rat, mouse, and chicken AKT.

AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.

Specifications

Antigen AKT
Applications ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.5M NaCl and 0.01% sodium azide; pH 7.2
Gene AKT1
Gene Accession No. P31749, P31750, P31751, P47196, P47197, Q60823, Q63484, Q9WUA6, Q9Y243
Gene Alias 2410016A19Rik; AI851531; Akt; Akt kinase; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT serine/threonine kinase 3; AKT/PKB; Akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; AKT2; AKT2 kinase; Akt3; AKT3 kinase; akt3a; AW554154; cb945; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; D930002M15Rik; DAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; dAkt1; DAKT1/PKB; DKFZp434N0250; Dmel\CG4006; Dmel_CG4006; Dpkb; DRAC-PK; DRAC-PK66; DRAC-PK85; HIHGHH; kinase Akt1; l(3)04226; l(3)89Bq; MGC99656; MPPH; MPPH2; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 1; murine thymoma viral (v-akt) oncogene homolog 2; Nmf350; pAkt; p-Akt; PKB; PKB alpha; PKB beta; PKB gamma; PKB/Akt; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBB; PKBbeta; PKBG; PKB-GAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B; Protein kinase B a
Gene Symbols AKT1, Akt2, Akt3
Host Species Rabbit
Immunogen Anti-AKT Pan Reactive Antibody was produced in rabbits by repeated immunizations with a cocktail containing recombinant human AKT1, AKT2, and AKT3 protein isoforms.
Quantity 25 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10000, 11651, 11652, 207, 208, 23797, 24185, 25233, 29414
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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