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AKT1 Monoclonal Antibody (OTI1G5), TrueMAB™, OriGene
SDP

Catalog No. 501674966
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50-167-4966 100 μL
50-254-0434 30 μL
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Catalog No. 50-167-4966 Supplier OriGene Supplier No. TA504238
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Description

Mouse Monoclonal Antibody

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.

Specifications

Antigen AKT1
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1G5
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene AKT1
Gene Accession No. P31749, P31750, P47196
Gene Alias AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Gene Symbols AKT1
Host Species Mouse
Immunogen Full length human recombit protein of human AKT1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11651, 207, 24185, 490878
Target Species Canine, Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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