AKT2 Mouse anti-Human, Biotin, Clone: OTI1A2, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA700010

Catalog No. 50-167-7583

Description

AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.

Specifications

• Antigen: AKT2
• Classification: Monoclonal
• Conjugate: Biotin
• Gene: AKT2
• Gene Alias: HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 208
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA
• Clone: OTI1A2
• Formulation: PBS with 10mg/ml BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: P31751
• Gene Symbols: AKT2
• Immunogen: Full length human recombit protein of human AKT2 produced in HEK293T cell.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a