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AKT2 Rat anti-Human, PE, Clone: 11F6.B2, Rockland™
SDP

Catalog No. 501991238
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50 μg
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50-199-1238 50 μg
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Catalog No. 50-199-1238 Supplier Rockland Immunochemicals Supplier No. 200508J35
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Description

Rat Monoclonal Antibody

Store vial at 4°C prior to restoration. Restore with deionized water (or equivalent). This product is stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Centrifuge product if not completely clear after standing at room temperature. Do not freeze after reconstitution. Store reagent in the dark. Use subdued lighting during handling and incubation of cells prior to analysis. Anti-AKT2 antibody is directed against human AKT2. The antibody detects both unphosphorylated and phosphorylated forms of the protein. Cross reactivity with AKT2 from other species has not been determined, however, the sequence of the immunogen shows 88% identity to mouse and 90% identity with rat, therefore, cross reactivity is expected.

Akt, protein kinase B (PKB), is a serine/threonine kinase, which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.

Specifications

Antigen AKT2
Applications Dot Blot, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 11F6.B2
Concentration 1 mg/mL
Conjugate PE
Formulation 0.02M potassium phosphate with 0.5M NaCl, 10 mg/mL BSA and no preservative; pH 7.2
Gene Akt2
Gene Accession No. P31751
Gene Alias 2410016A19Rik; AKT serine/threonine kinase 2; Akt2; AKT2 kinase; AW554154; HIHGHH; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 2; PKB; PKB beta; PKBB; PKBbeta; PRKBB; Protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; thymoma viral proto-oncogene 2; v-akt murine thymoma viral oncogene homolog 2
Gene Symbols Akt2
Host Species Rat
Immunogen Anti-AKT2 Antibody was produced in rat by repeated immunizations with a synthetic peptide corresponding to internal residues of human AKT2 protein.
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 208
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2a κ
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