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Description
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
Specifications
Specifications
| Antigen | AKT3 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 154CT4.5.3 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against human AKT3. |
| Dilution | Immunohistochemistry (1:50-1:100) Western Blot (1:100-1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene Alias | DKFZp434N0250/PKB-GAMMA/PKBG/PRKBG/RAC-PK-gamma/RAC-gamma/STK-2 |
| Gene Symbols | AKT3 |
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