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  5. Tocris Bioscience™ Akti-1/2

Tocris Bioscience™ Akti-1/2
GREENER_CHOICE

Catalog No. 577350
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective dual Akt1 and 2 inhibitor

Akti-1/2 is a potent and selective dual Akt1 and 2 inhibitor (IC50 values are 50 and 210 nM, respectively). Selective for Akt1 and 2 over a panel of other tyrosine and serine/threonine kinases. Sensitizes LnCaP cells to TRAIL (TNF-related apoptosis-inducing ligand) induced apoptosis. Also enhances CAR and TCR retroviral transduction of human T cells. Active in vivo.

Specifications

Chemical Name or Material 1,3-Dihydro-1-[1-[[4-(6-phenyl-1 H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2 H-benzimidazol-2-one
CAS 612847-09-3
Synonym Akt Inhibitor VIII
Quantity 50 mg
Target Akt (Protein Kinase B) Inhibitors
Molecular Formula C34H29N7O
Formula Weight 551.64
Purity 98%
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