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Invitrogen™ ALAD Polyclonal Antibody
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Catalog No. PIPA5107056
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PIPA5107056 100 μL
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Catalog No. PIPA5107056 Supplier Invitrogen™ Supplier No. PA5107056
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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Yeast: 86%; Zebrafish: 86%.

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALAD
Applications Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene ALAD
Gene Accession No. P13716
Gene Alias Alad; ALADH; ALADR; aminolevulinate dehydratase; aminolevulinate, delta-, dehydratase; aminolevulinatedelta-dehydratase; delta - aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase; Lv; PBGS; Porphobilinogen synthase; testicular tissue protein Li 95
Gene Symbols ALAD
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human ALAD (aa 192-242).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 210
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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