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Invitrogen™ ALAD Polyclonal Antibody
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Catalog No. PIPA554564
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PIPA554564 100 μL
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Catalog No. PIPA554564 Supplier Invitrogen™ Supplier No. PA554564
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLIFGVPSRV PKDERGSAAD SEESPAIEAI HLLRKTFPNL LVACDVCLCP YTSHGHCGLL SENGAFRAEE SRQRLAEVAL AYA Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALAD
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ALAD
Gene Accession No. P13716
Gene Alias Alad; ALADH; ALADR; aminolevulinate dehydratase; aminolevulinate, delta-, dehydratase; aminolevulinatedelta-dehydratase; delta - aminolevulinic acid dehydratase; delta-aminolevulinic acid dehydratase; Lv; PBGS; Porphobilinogen synthase; testicular tissue protein Li 95
Gene Symbols ALAD
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ALAD. Recombinant protein control fragment (Product #RP-93004).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 210
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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