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ALAD Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988156
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50-198-8156 100 μL
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Catalog No. 50-198-8156 Supplier Bioss Supplier No. BS7954R
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Rabbit Polyclonal Antibody

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

Antigen ALAD
Applications Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ALAD
Gene Accession No. P13716
Gene Alias Alad; ALADH; ALADR; aminolevulinate dehydratase; aminolevulinate, delta-, dehydratase; aminolevulinatedelta-dehydratase; delta - aminolevulinic acid dehydratase; Delta-aminolevulinic acid dehydratase; Lv; PBGS; Porphobilinogen synthase; testicular tissue protein Li 95
Gene Symbols ALAD
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ALAD.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 210
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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