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Invitrogen™ alanyl-tRNA Synthetase Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559335

Catalog No. PIPA559335


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Description

Description

Immunogen sequence: DRASKADVQK RVLEKTKQFI DSNPNQPLVI LEMESGASAK ALNEALKLFK MHSPQTSAML FTVDNEAGKI TCLCQVPQNA ANRGLKASEW VQQVSGLMDG KGGGKD Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E. coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

alanyl-tRNA Synthetase
Polyclonal
Unconjugated
AARS1
Aars; AI316495; alanine tRNA ligase 1, cytoplasmic; alanine--tRNA ligase, cytoplasmic; alanine--tRNA ligase, cytoplasmic {ECO:0000255; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255; alanyl-tRNA synthetase, cytoplasmic; alaRS; alaRS {ECO:0000255; C76919; CMT2N; EIEE29; HAMAP-Rule:MF_03133}; Protein sticky; Renal carcinoma antigen NY-REN-42; sti
Rabbit
Antigen Affinity Chromatography
RUO
16, 234734, 292023
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P49588, P50475, Q8BGQ7
AARS1
Recombinant protein corresponding to Human alanyl-tRNA Synthetase. Recombinant protein control fragment (Product #RP-98616).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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