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Invitrogen™ ALAS2 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121007

Catalog No. PIPA5121007


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Description

Description

Positive test controls include: 293T, Mouse liver, Mouse spleen, Mouse lung. The target is usually found in the following locations: Mitochondrion matrix. Immunogen sequence: VKTHQFLFGI GRCPILATQG PNCSQIHLKA TKAGGDSPSW AKGHCPFMLS ELQDGKSKIV QKAAPEVQED VKAFKTGNYV FSYDQFFRDK IMEKKQDHTY RVFKTVNRWA DAYPFAQHFS EASVASKDVS VWCSNDYLGM SRHPQVLQAT QETLQRHGAG AGGTRNISGT SKFHVELEQE LAELHQKDSA LLFSSCFVAN DSTLFTLAKI LPGCEIYSDA GNHASMIQGI RNSGAAKFVF RHNDPDHLKK LLEKSNPKIP KIVAFETVHS M.

ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ALAS2
Polyclonal
Unconjugated
ALAS2
5'-aminolevulinate synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase 2; ALAS; Alas2; Alas-2; alas2 protein; Alase; ALAS-E; Aminolevulinate synthase 2, delta; aminolevulinate synthase erythroid specific isoform; aminolevulinate, delta-, synthase 2; aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); aminolevulinate, delta-, synthetase 2; aminolevulinic acid synthase 2, erythroid; ANH1; ASB; cb1063; Delta-ALA synthase 2; delta-ALA synthetase; delta-ALA synthetase 2; delta-aminolevulinate synthase 2; erythroid aminolevulinate synthase; erythroid-specific ALAS; erythroid-specific delta-aminolevulinate synthase ALAS-E; heme biosynthetic enzyme; PRO2399; RP5-884M20.1; sau; sauternes; si:dkey-24f17.4; SIDBA1; XLDPP; XLEPP; XLSA
Rabbit
Affinity Chromatography
RUO
11656, 212, 25748
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
1.28 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08680, P22557, Q63147
ALAS2
Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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