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Invitrogen™ ALAS2 Polyclonal Antibody

Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5121007
Description
Positive test controls include: 293T, Mouse liver, Mouse spleen, Mouse lung. The target is usually found in the following locations: Mitochondrion matrix. Immunogen sequence: VKTHQFLFGI GRCPILATQG PNCSQIHLKA TKAGGDSPSW AKGHCPFMLS ELQDGKSKIV QKAAPEVQED VKAFKTGNYV FSYDQFFRDK IMEKKQDHTY RVFKTVNRWA DAYPFAQHFS EASVASKDVS VWCSNDYLGM SRHPQVLQAT QETLQRHGAG AGGTRNISGT SKFHVELEQE LAELHQKDSA LLFSSCFVAN DSTLFTLAKI LPGCEIYSDA GNHASMIQGI RNSGAAKFVF RHNDPDHLKK LLEKSNPKIP KIVAFETVHS M.
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications
ALAS2 | |
Polyclonal | |
Unconjugated | |
ALAS2 | |
5'-aminolevulinate synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase 2; ALAS; Alas2; Alas-2; alas2 protein; Alase; ALAS-E; Aminolevulinate synthase 2, delta; aminolevulinate synthase erythroid specific isoform; aminolevulinate, delta-, synthase 2; aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); aminolevulinate, delta-, synthetase 2; aminolevulinic acid synthase 2, erythroid; ANH1; ASB; cb1063; Delta-ALA synthase 2; delta-ALA synthetase; delta-ALA synthetase 2; delta-aminolevulinate synthase 2; erythroid aminolevulinate synthase; erythroid-specific ALAS; erythroid-specific delta-aminolevulinate synthase ALAS-E; heme biosynthetic enzyme; PRO2399; RP5-884M20.1; sau; sauternes; si:dkey-24f17.4; SIDBA1; XLDPP; XLEPP; XLSA | |
Rabbit | |
Affinity Chromatography | |
RUO | |
11656, 212, 25748 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
1.28 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P08680, P22557, Q63147 | |
ALAS2 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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