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Invitrogen™ ALAS2 Polyclonal Antibody
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Catalog No. PIPA5121007
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100 μL
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PIPA5121007 100 μL
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Catalog No. PIPA5121007 Supplier Invitrogen™ Supplier No. PA5121007
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Description

Rabbit Polyclonal Antibody

Positive test controls include: 293T, Mouse liver, Mouse spleen, Mouse lung. The target is usually found in the following locations: Mitochondrion matrix. Immunogen sequence: VKTHQFLFGI GRCPILATQG PNCSQIHLKA TKAGGDSPSW AKGHCPFMLS ELQDGKSKIV QKAAPEVQED VKAFKTGNYV FSYDQFFRDK IMEKKQDHTY RVFKTVNRWA DAYPFAQHFS EASVASKDVS VWCSNDYLGM SRHPQVLQAT QETLQRHGAG AGGTRNISGT SKFHVELEQE LAELHQKDSA LLFSSCFVAN DSTLFTLAKI LPGCEIYSDA GNHASMIQGI RNSGAAKFVF RHNDPDHLKK LLEKSNPKIP KIVAFETVHS M.

ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALAS2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ALAS2
Gene Accession No. P08680, P22557, Q63147
Gene Alias 5'-aminolevulinate synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase 2; ALAS; Alas2; Alas-2; alas2 protein; Alase; ALAS-E; Aminolevulinate synthase 2, delta; aminolevulinate synthase erythroid specific isoform; aminolevulinate, delta-, synthase 2; aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); aminolevulinate, delta-, synthetase 2; aminolevulinic acid synthase 2, erythroid; ANH1; ASB; cb1063; Delta-ALA synthase 2; delta-ALA synthetase; delta-ALA synthetase 2; delta-aminolevulinate synthase 2; erythroid aminolevulinate synthase; erythroid-specific ALAS; erythroid-specific delta-aminolevulinate synthase ALAS-E; heme biosynthetic enzyme; PRO2399; RP5-884M20.1; sau; sauternes; si:dkey-24f17.4; SIDBA1; XLDPP; XLEPP; XLSA
Gene Symbols ALAS2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11656, 212, 25748
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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