Alcohol Oxidase, MP Biomedicals™

Description

Plays a major role in the metabolism of methanol, resulting in the formation of formaldehyde. Alcohol Oxidase, MP Biomedicals is used for qualitative and quantitative determination of methanol or ethanol (blood alcohol) by colorimetric procedures, and can

Alcohol oxidase has been detected in several strains of yeast (such as Candida, Pichia and Hansenula) that utilize methanol as a sole carbon and energy source. Some of these enzymes have been isolated and partially characterized. Monomers are synthesized in the cytosol and assembled into octomers in the peroxisome. Octomerization is thought to be chaparone mediated.

Alcohol oxidase is of interest for the study of protein translocation into peroxisomes. It catalyzes the oxidation of an alcohol to an aldehyde and hydrogen peroxide.

• Catalyzes the oxidation of short-chain, primary, aliphatic alcohols to their respective aldehydes (it has the highest affinity for methanol)
• Involved in the metabolism of methanol, which is important for yeasts that utilize methanol as their sole energy source
• Primarily found in the peroxisome, but may be present in the cytoplasm as well
• One unit will oxidize 1.0 μmole of methanol to formaldehyde per minute at pH 7.5 at 25°C

Specifications

Chemical Identifiers

• CAS: 9073-63-6
• Molecular Formula: C10H25NO2
• Molecular Weight (g/mol): 191.315
• InChI Key: LJCNDNBULVLKSG-UHFFFAOYSA-N
• Synonym: oxidase, alcohol, bis butane ; glycine
• PubChem CID: 73555276
• IUPAC Name: 2-aminoacetic acid;butane
• SMILES: CCCC.CCCC.C(C(=O)O)N

• Quantity: 250 U
• Formula Weight: about 630,000g/mol
• Physical Form: Frozen Liquid

Safety and Handling

Recommended Storage

Freeze at –20°C

WARNING: Reproductive Harm - www.P65Warnings.ca.gov