Invitrogen™ ALDH1B1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109378

Catalog No. PIPA5109378

Description

Immunogen sequence: NLKRVTLELG GKSPSIVLAD ADMEHAVEQC HEALFFNMGQ CCCAGSRTFV EESIYNEFLE RTVEKAKQRK VGNPFELDTQ QGPQVDKEQF ERVLGYIQLG QKEGAKLLCG GERFGERGFF IKPTVFGGVQ DDMRIAKEEI FGPVQPLFKF KKIEEVVERA NNTRYGLAAA VFTRDLDKAM YFTQALQAGT VWVNTYNIVT CHTPFGGFKE SGNGRELGED GLKAYTEVKT VTIKVPQKNS.

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. Alcohol drinking habits and cardiovascular disease risk factors may be associated with ALDH gene variants. ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517 amino acid mitochondrial protein that is expressed in the liver, testis and to a lesser extent in brain. ALDH1B1 belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.

Specifications

• Antigen: ALDH1B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALDH1B1
• Gene Alias: 2700007F14Rik; acetaldehyde dehydrogenase 5; aldehyde dehydrogenase 1 family member B1; aldehyde dehydrogenase 1 family, member B1; aldehyde dehydrogenase 1B1; aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1; aldehyde dehydrogenase X, mitochondrial; ALDH class 2; ALDH1B1; ALDH5; ALDHX; MGC2230
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 219, 298079, 72535
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.31 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P30837, Q66HF8, Q9CZS1
• Gene Symbols: ALDH1B1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG