Invitrogen™ ALDH1B1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528554

Catalog No. PIPA528554

Description

Recommended positive controls: A431. Predicted reactivity: Mouse (94%), Rat (94%), Chimpanzee (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. Alcohol drinking habits and cardiovascular disease risk factors may be associated with ALDH gene variants. ALDH1B1 (Aldehyde dehydrogenase family 1 member B1), also known as ALDH5 or ALDHX (Aldehyde dehydrogenase X, mitochondrial), is a 517 amino acid mitochondrial protein that is expressed in the liver, testis and to a lesser extent in brain. ALDH1B1 belongs to the aldehyde dehydrogenase family and may play a major role in ethanol detoxification.

Specifications

• Antigen: ALDH1B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALDH1B1
• Gene Alias: 2700007F14Rik; acetaldehyde dehydrogenase 5; aldehyde dehydrogenase 1 family member B1; aldehyde dehydrogenase 1 family, member B1; aldehyde dehydrogenase 1B1; aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1; aldehyde dehydrogenase X, mitochondrial; ALDH class 2; ALDH1B1; ALDH5; ALDHX; MGC2230
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 219, 72535
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.87 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P30837, Q9CZS1
• Gene Symbols: ALDH1B1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 226 and 517 of Human ALDH1B1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov