Invitrogen™ ALDH2 Recombinant Rabbit Monoclonal Antibody (1J9I8)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535122

Catalog No. PIMA535122

Description

Immunogen sequence: HRGRLLNRLA DLIERDRTYL AALETLDNGK PYVISYLVDL DMVLKCLRYY AGWADKYHGK TIPIDGDFFS YTRHEPVGVC GQIIPWNFPL LMQAWKLGPA L.

ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.

Specifications

• Antigen: ALDH2
• Classification: Recombinant Monoclonal
• Concentration: 0.45 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05091, P11884, P47738
• Gene Symbols: Aldh2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ALDH2 (P05091).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 1J9I8
• Conjugate: Unconjugated
• Gene: Aldh2
• Gene Alias: acetaldehyde dehydrogenase 2; Ahd1; Ahd-1; Ahd5; Ahd-5; AHD-M1; aldehyde dehydrogenase 2 family (mitochondrial); aldehyde dehydrogenase 2, mitochondrial; aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH1; ALDH2; ALDH-E2; ALDHI; ALDM; EC 1.2.1.3; liver mitochondrial ALDH; MGC1806; mitochondrial aldehyde dehydrogenase; nucleus-encoded mitochondrial aldehyde dehydrogenase 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11669, 217, 29539
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid