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Invitrogen™ ALDH3A2 Monoclonal Antibody (151CT1.3.1)
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Catalog No. PIMA537474
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PIMA537474 100 μL
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Catalog No. PIMA537474 Supplier Invitrogen™ Supplier No. MA537474
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Description

Mouse Monoclonal Antibody

ALDH3A2 Monoclonal Antibody for Western Blot, IHC (P)

Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALDH3A2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 151CT1.3.1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.09% sodium azide; pH 7.4
Gene ALDH3A2
Gene Accession No. P51648
Gene Alias Ahd3; Ahd-3; Ahd-3r; Ahd3-r; AI194803; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 10; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A2; aldehyde dehydrogenase 3 family, member A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase; aldehyde dehydrogenase family 3, subfamily A2; ALDH10; Aldh3; Aldh3a2; Aldh4; Aldh4-r; DKFZp686E23276; FALDH; fatty aldehyde dehydrogenase; Fatty aldehyde dehydrogenase-like protein; FLJ20851; microsomal aldehyde dehydrogenase; msALDH; QccE-15682; SLS
Gene Symbols ALDH3A2
Host Species Mouse
Immunogen ALDH3A2 recombinant protein.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 224
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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