Invitrogen™ ALDH3A2 Monoclonal Antibody (OTI2A7)

Catalog No.	Quantity
PIMA525632	100 μL

Catalog No. PIMA525632 Supplier Invitrogen™ Supplier No. MA525632

Description

Mouse Monoclonal Antibody

ALDH3A2 Monoclonal Antibody for Flow, IHC (P), Western Blot

Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.

Specifications

• Antigen: ALDH3A2
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2A7
• Concentration: 0.62 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ALDH3A2
• Gene Accession No.: P51648
• Gene Alias: Ahd3; Ahd-3; Ahd-3r; Ahd3-r; AI194803; alcohol dehydrogenase family 3, subfamily A2; aldehyde dehydrogenase 10; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A2; aldehyde dehydrogenase 3 family, member A2; aldehyde dehydrogenase 3A2; aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A2; aldehyde dehydrogenase family 3 member A2; fatty aldehyde dehydrogenase; aldehyde dehydrogenase family 3, subfamily A2; ALDH10; Aldh3; Aldh3a2; Aldh4; Aldh4-r; DKFZp686E23276; FALDH; fatty aldehyde dehydrogenase; Fatty aldehyde dehydrogenase-like protein; FLJ20851; microsomal aldehyde dehydrogenase; msALDH; QccE-15682; SLS
• Gene Symbols: ALDH3A2
• Host Species: Mouse
• Immunogen: Full length human recombinant protein of ALDH3A2 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 224
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b