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Invitrogen™ ALDH5A1 Polyclonal Antibody, Biotin
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Catalog No. PIPA5142621
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100 μg
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PIPA5142621 100 μg
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Catalog No. PIPA5142621 Supplier Invitrogen™ Supplier No. PA5142621
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ALDH5A1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene ALDH5A1
Gene Accession No. P51649
Gene Alias 6330403E24Rik; Ahd1; Ahd-1; aldehyde dehydrogenase 1, mitochondrial; aldehyde dehydrogenase 5 family member A1; aldehyde dehydrogenase 5 family, member A1; aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase); aldehyde dehydrogenase family 5 member A1; aldehyde dehydrogenase family 5, subfamily A1; ALDH5A1; aldhehyde dehydrogenase family 5, subfamily A1; D630032B01Rik; mitochondrial succinate semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; OTTMUSG00000000613; SSADH; SSDH; Ssdh1; Succinate-semialdehyde dehydrogenase, mitochondrial; succinic semialdehyde dehydrogenase
Gene Symbols ALDH5A1
Host Species Goat
Immunogen Peptide with sequence C-SQDPAQIWRVAE (aa 472-483).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7915
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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