Invitrogen™ Aldolase A/B/C Monoclonal Antibody (E9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA547476

Catalog No. PIMA547476

Description

Aldolase A/B/C Monoclonal Antibody for Western Blot, ICC/IF, IHC

Aldolases are important glycolytic cytosolic enzymes which catalyse the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate. There are three aldolase isozymes coded by three distinct genes in mammals, namely aldolases A, B, and C. Aldolase A is heavily expressed in muscle enzyme and aldolase B is heavily expressed in liver and is regarded as a liver specific enzyme. In the adult, aldolase C is the brain-specific isozyme expressed in astrocytes and a few classes of neurons, notably Purkinje cells. Appropriate antibodies to aldolase C are therefore useful to identify astrocytes in cell culture and sectioned material, and the enzyme may be over expressed in some forms of cancer.

Specifications

• Antigen: Aldolase A/B/C
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 5mM sodium azide
• Gene Accession No.: P00884, P04075, P05062, P05063, P05064, P05065, P09117, P09972, Q91Y97
• Gene Symbols: ALDOA, ALDOB, ALDOC
• Immunogen: Recombinant human full-length aldolase C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: E9
• Conjugate: Unconjugated
• Gene: ALDOC
• Gene Alias: ALDA; ALDB; ALDC
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 11674, 11676, 226, 229, 230, 230163, 24189, 24190, 24191
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid