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Invitrogen™ Aldolase A/B/C Monoclonal Antibody (E9)
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Catalog No. PIMA547476
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500 μL
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PIMA547476 100 μL
PIMA547377 500 μL
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Catalog No. PIMA547476 Supplier Invitrogen™ Supplier No. MA547476
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Mouse Monoclonal Antibody

Aldolase A/B/C Monoclonal Antibody for Western Blot, ICC/IF, IHC

Aldolases are important glycolytic cytosolic enzymes which catalyse the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate. There are three aldolase isozymes coded by three distinct genes in mammals, namely aldolases A, B, and C. Aldolase A is heavily expressed in muscle enzyme and aldolase B is heavily expressed in liver and is regarded as a liver specific enzyme. In the adult, aldolase C is the brain-specific isozyme expressed in astrocytes and a few classes of neurons, notably Purkinje cells. Appropriate antibodies to aldolase C are therefore useful to identify astrocytes in cell culture and sectioned material, and the enzyme may be over expressed in some forms of cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aldolase A/B/C
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone E9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene ALDOC
Gene Accession No. P00884, P04075, P05062, P05063, P05064, P05065, P09117, P09972, Q91Y97
Gene Alias ALDA; ALDB; ALDC
Gene Symbols ALDOA, ALDOB, ALDOC
Host Species Mouse
Immunogen Recombinant human full-length aldolase C.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11674, 11676, 226, 229, 230, 230163, 24189, 24190, 24191
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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