Invitrogen™ Aldolase A Monoclonal Antibody (6H8)

Catalog No.	Quantity
PIMA549283	100 μg

Catalog No. PIMA549283 Supplier Invitrogen™ Supplier No. MA549283

Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HEPG2 whole cell, human A549 whole cell, human PC-3 whole cell, human Hek293 whole cell. IHC: human liver cancer tissue, human breast cancer tissue, human rectal cancer tissue. ICC/IF: HEPG2 cell. Flow: SiHa cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.

Specifications

• Antigen: Aldolase A
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 6H8
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: ALDOA
• Gene Accession No.: P04075
• Gene Alias: ALDA; Aldo1; Aldo-1; ALDOA; Aldolase 1; aldolase 1, A isoform; aldolase A; aldolase A, fructose-bisphosphate; aldolase, fructose-bisphosphate A; epididymis secretory sperm binding protein Li 87p; fructose-1,6-bisphosphate triosephosphate-lyase; fructose-bisphosphate aldolase A; GSD12; HEL-S-87p; Lung cancer antigen NY-LU-1; muscle-type aldolase; RNALDOG5; unnamed protein product
• Gene Symbols: ALDOA
• Host Species: Mouse
• Immunogen: E.coli-derived human Aldolase/ALDOA recombinant protein (Position: E50-Y364).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 226
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b