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Invitrogen™ Aldosterone Polyclonal Antibody
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Catalog No. PIPA185149
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PIPA185149 1 mL
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Catalog No. PIPA185149 Supplier Invitrogen™ Supplier No. PA185149
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Description

Rabbit Polyclonal Antibody

PA1-85149 shows <1% cross-reactivity with Androstenedione, Corticosterone, DHEA or Desoxycorticosterone, as determined using a competitive ELISA with 400 ng of aldosterone-3-BSA per well. This antibody has been cross-absorbed with BSA. Rabbit anti Aldosterone antibody recoognizes aldosterone, a hormone produced by the adrenal glands that helps regulate blood pressure through increasing both the release of potassium and the uptake of water and sodium by the kidneys.

Aldosterone is a hormone produced by the adrenal glands that helps regulate blood pressure through increasing both the release of potassium and the uptake of water and sodium by the kidneys. It is essential for sodium conservation in the kidney, salivary glands, sweat glands and colon. It plays a central role in the regulation of the plasma sodium (Na+), the extracellular potassium (K+) and arterial blood pressure. It does so mainly by acting on the mineralocorticoid receptors in the distal tubules and collecting ducts of the nephron. It influences the reabsorption of sodium and excretion of potassium (from and into the tubular fluids, respectively) of the kidney, thereby indirectly influencing water retention or loss, blood pressure and blood volume. When dysregulated, aldosterone is pathogenic and contributes to the development and progression of cardiovascular and renal disease. Aldosterone has exactly the opposite function of the atrial natriuretic hormone secreted by the heart.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aldosterone
Applications ELISA
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Host Species Rabbit
Immunogen Aldosterone-3-CMO-BSA.
Purification Method Protein A
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Chemical
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