Invitrogen™ ALG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559606

Catalog No. PIPA559606

Description

Immunogen sequence: LYTPSNEHFG IVPLEAMYMQ CPVIAVNSGG PLESIDHSVT GFLCEPDPVH FSEAIEKFIR EPSLKATMGL AGRARVKEKF SPEAFTEQLY RYVTK Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%.

ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1, 3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1, 3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).

Specifications

• Antigen: ALG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ALG2
• Gene Alias: 1110018A23Rik; 1300013N08Rik; Alg2; ALG2 alpha-1,3/1,6-mannosyltransferase; ALG2, alpha-1,3/1,6-mannosyltransferase; ALPG2; alpha-1,3/1,6-mannosyltransferase ALG2; alpha-1,3-mannosyltransferase ALG2; asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog; asparagine-linked glycosylation protein 2 homolog; CDGIi; CMS14; CMSTA3; FLJ14511; FLJ14511 protein; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; hALPG2; homolog of yeast ALG2; im:7145131; LOW QUALITY PROTEIN: alpha-1,3/1,6-mannosyltransferase ALG2; MNCb-5081; NET38; UNQ666/PRO1298
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 85365
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H553
• Gene Symbols: ALG2
• Immunogen: Recombinant protein corresponding to Human ALG2. Recombinant protein control fragment (Product #RP-98411).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG