Invitrogen™ Alivin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562894

Catalog No. PIPA562894

Description

Immunogen sequence: AQVGERLMVH CDSKTGNANT DFIWVGPDNR LLEPDKEMEN FYVFHNGSLV IESPRFEDAG VYSCIAMNKQ RLLNETVDVT INVSNFTVSR S Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 82%.

A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.

Specifications

• Antigen: Alivin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Amigo2
• Gene Alias: adhesion molecule with Ig like domain 2; adhesion molecule with Ig-like domain 2; AI415330; Ali1; alivin 1; alivin-1; amigo2; AMIGO-2; amigo2 {ECO:0000312; amphoterin induced gene 2; amphoterin induced gene and ORF 2; amphoterin-induced protein 2; AW208913; DEGA; differentially expressed in gastric adenocarcinoma; differentially expressed in gastric adenocarcinomas; EMBL:AAO48951.1}; transmembrane protein AMIGO2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 347902
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86SJ2
• Gene Symbols: Amigo2
• Immunogen: Recombinant protein corresponding to Human Alivin 1. Recombinant protein control fragment (Product #RP-101320).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG