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Invitrogen™ Alivin 1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA566268
Description
Immunogen sequence: CPCKCKTKRQK NMLHQSNAHS SILSPGPASD ASADERKAGA GKRVVFLEPL KDTAAGQNGK VRLFPSEAVI AEGILKST Highest antigen sequence identity to the following orthologs - mouse 86%, rat 80%.
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.
Specifications
Alivin 1 | |
Polyclonal | |
Unconjugated | |
Amigo2 | |
adhesion molecule with Ig like domain 2; adhesion molecule with Ig-like domain 2; AI415330; Ali1; alivin 1; alivin-1; amigo2; AMIGO-2; amigo2 {ECO:0000312; amphoterin induced gene 2; amphoterin induced gene and ORF 2; amphoterin-induced protein 2; AW208913; DEGA; differentially expressed in gastric adenocarcinoma; differentially expressed in gastric adenocarcinomas; EMBL:AAO48951.1}; transmembrane protein AMIGO2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
347902 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q86SJ2 | |
Amigo2 | |
Recombinant Human Alivin 1. Recombinant protein control fragment (Product #RP-106951). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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