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Alkaline Phosphatase Mouse anti-Human, Brilliant Violet 786, Clone: B4-78, BD Optibuild™

Catalog No. BDB742714 Shop All BD Biosciences Products
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BDB742714 50 μg
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Catalog No. BDB742714 Supplier BD Biosciences Supplier No. 742714
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Description

Mouse Monoclonal Antibody

The B4-78 monoclonal antibody reacts with the tissue-nonspecific isozyme of alkaline phosphatase. Alkaline phosphatases are membrane-bound glycoproteins. Four isozymes of alkaline phosphatase exist in humans: placental, placental-like, intestinal, and liver/bone/kidney. Liver/bone/kidney alkaline phosphatase is also known as tissue-nonspecific alkaline phosphatase (TNAP). Human embryonic stem cells and embryonic carcinoma cells express high levels of tissue-nonspecific alkaline phosphatase that decrease upon differentiation. Genetic and biochemical studies suggest that TNAP plays a role in skeletal mineralization.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter). BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm. BV786 offers a bright choice for the 6th detector off the violet laser.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Alkaline Phosphatase
Classification Monoclonal
Clone B4-78
Concentration 0.2mg/mL
Conjugate Brilliant Violet 786
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias Bone/Kidney/Liver Alkaline Phosphatase, TNAP, TNSALP, AP-TNAP, ALPL
Host Species Mouse
Immunogen Human Bone Alkaline Phosphatase
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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